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Anti-CD3 Monoclonal Antibody (Clone:145-2C11)-APC Conjugated
30-1751
0,1 mg
€628
Legenda image
Surface staining of CD3 in murine splenocytes with anti-CD3 (145-2C11) APC.
Product description
CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.
Specifications
Applications
FC, IP, IHC-Fr, ICC, FUNC
Host
Hamster
Clonality
Monoclonal
Clone
145-2C11
Isotype
Hamster IgG
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C
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Anti-CD3 Monoclonal Antibody (Clone:145-2C11)-APC Conjugated
30-1751
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Anti-CD3 Monoclonal Antibody (Clone:145-2C11)-APC Conjugated
30-1751
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