Legenda image
FLOW analysis of Balb C mouse splenocytes stimulated with LPS (3 days) stained with purified CD80 (clone 16-10A1, red) or Armenian hamster IgG isotype control (green), followed by goat anti-Armenian hamster IgG PE.
Product description
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Specifications
Applications
FC
Host
Hamster
Clonality
Monoclonal
Clone
16-10A1
Isotype
Hamster IgG2
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Anti-CD80 Monoclonal Antibody (Clone:16-10A1)

30-1438

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Anti-CD80 Monoclonal Antibody (Clone:16-10A1)

30-1438

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