Product description
Daxx is an apoptosis-modulating death domain-associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).
Specifications
Applications
WB, ICC
Host
Mouse
Clonality
Monoclonal
Clone
DAXX-01
Isotype
Mouse IgG1
Supplier
Abeomics
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Productname

Anti-Daxx / DAP6 Monoclonal Antibody (Clone:DAXX-01)

30-1228

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Productname

Anti-Daxx / DAP6 Monoclonal Antibody (Clone:DAXX-01)

30-1228

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