Hypocrellin A is a perylenequinoid that has been found in Shiraia bambusicola and has diverse biological activities.{52379,52380} It is active against C. albicans, C. parapsilosis, and C. tropicalis fungi (IC50s = 0.65, 1, and 85 ug/ml, respectively), as well as S. aureus, methicillin-resistant S. aureus (MRSA), P. aeruginosa, and M. intracellulare bacteria (IC50s = 3, 7, 10, and 2.5 ug/ml, respectively).{52379} Hypocrellin A is also active against L. donovani promastigotes (IC50 = 0.27 ug/ml). Upon photoactivation with UV radiation, hypocrellin A induces production of reactive oxygen species and apoptosis and reduces cell viability of A549 cancer cells.{52380}
Specifications
Size
10 mg
CAS number
77029-83-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C