Product description
8-M-PDOT is a melatonin receptor 2 (MT2) agonist (Ki = 1.12 nM).{26021} It is 5.2-fold selective for MT2 over MT1 receptors in a radioligand binding assay. Striatal microinfusion of 8-M-PDOT (10 ?g/?l) increases the percentage of time spent in the open arms of the elevated plus maze, indicating anxiolytic-like activity, in a rat model of rotenone-induced Parkinson's disease.{47781}
Specifications
CAS number
134865-70-6
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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