Product description
17a-hydroxy Pregnenolone is a metabolite of pregnenolone (Item No. 19864) and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; Item No. 15728).{53115} It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17a-hydroxy pregnenolone are elevated in patients with type II 3B-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.{53116}
Specifications
CAS number
387-79-1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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