4-Fluoro-L-phenylalanine

4-Fluoro-L-phenylalanine is a non-proteinogenic amino acid and an inhibitor of protein synthesis.{47782,47783} It inhibits growth of MCF-7 breast cancer cells (IC50 = 11.8 ?M).{47782} 4-Fluoro-L-phenylalanine reversibly inhibits stomatin-induced T. vorax macrostomal differentiation in a concentration-dependent manner.{47783} It has been used to replace phenylalanine residues in polypeptides for determining site-specific solvent accessibility by 19F-NMR.{47784}