Product description
1,10-Phenanthrine is a metal chelator and inhibitor of metalloproteases.{48730,48731,48732} It inhibits zinc-dependent hydrolysis of Fa-Gly-Leu-NH2 by B. subtilis neutral protease and B. thermoproteolyticus thermolysin.{48730} 1,10-Phenanthrine is fungistatic against P. verrucosa (MIC = 0.8 ?g/ml) and inhibits zinc-induced P. verrucosa metallo-type peptidase activity in a concentration-dependent manner.{48731} It induces uncoupling of and inhibits egg production by adult S. mansoni worm pairs in vitro when used at concentrations ranging from 0.5 to 150 ?M.{48732} 1,10-Phenanthrine (20 mg/kg per day) reduces worm burden in a mouse model of S. mansoni infection.
Specifications
CAS number
5144-89-8
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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1,10-Phenanthroline (hydrate)

28951-10

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1,10-Phenanthroline (hydrate)

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