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4-oxo-27-TBDMS Withaferin A
28323-5
5 mg
€293
Product description
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A (Item No. 11352) that has anticancer activity.{50042} It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 µM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 µM). It is selective for A2780 cells over non-cancerous ARPE19 cells (IC50 = 1,660 µM). 4-oxo-27-TBDMS Withaferin A induces DNA fragmentation in A2780 cells.
Specifications
CAS number
1214886-31-3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C
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4-oxo-27-TBDMS Withaferin A
28323-5
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4-oxo-27-TBDMS Withaferin A
28323-5
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