Product description
(+-)-Ketoprofen-d3 is intended for use as an internal standard for the quantification of (+-)-ketoprofen (Item No. 10006661) by GC- or LC-MS. (+-)-Ketoprofen is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID).{1286} It inhibits human recombinant COX-1 and COX-2 with IC50 values of 0.5 and 2.33 µM, respectively. In vivo, (+-)-ketoprofen reduces carrageenan-induced paw edema and increases latency to paw withdrawal in the hot plate test in rats when administered using a sustained-release implant.{42815} Formulations containing (+-)-ketoprofen have been used to treat pain and inflammation in osteoarthritis.
Specifications
CAS number
159490-55-8
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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