Product description
3,4-Dihydroxybenzaldehyde is a polyphenol that has been found in S. miltiorrhiza and has diverse biological activities, including antibacterial, antioxidative, and anticancer properties.{45267,45268,45269,45270} It is active against methicillin-resistant S. aureus (MRSA) when used at a concentration of 0.01 µg/ml.{45268} It prevents hexavalent chromium-induced formation of reactive oxygen species (ROS) and reactive nitrogen species (RNS) in a concentration-dependent manner and increases glutathione (GSH) levels in isolated human erythrocytes.{45267} 3,4-Dihydroxybenzaldehyde selectively inhibits human DNA topoisomerase II (IC50 = 150 µM) over human topoisomerase I and a variety of mammalian polymerases (IC50s = >200 µM).{45269} It inhibits proliferation of HT-29 cells when used at a concentration of 362 µM but not HCT116 cells at a concentration of 100 µM.{45270,45269}
Specifications
CAS number
139-85-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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