Product description
(+-)-y-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties.{15114,15117,8680} It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays.{15114,15117} It also reduces the synthesis of prostaglandin E2 (PGE2; Item No. 14010) induced by LPS in RAW 264.7 macrophages and by IL-1B in A549 cells (IC50s = 7.5 and 4 ?M, respectively).{8680} (+-)-y-Tocopherol (10 ?M) inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1B. Serum levels of (+-)-y-tocopherol are decreased in patients with cardiovascular disease.{15114} [Matreya, LLC. Catalog No. 1073]
Specifications
CAS number
7616-22-0
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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