Product description
8-dehydro Cholesterol (8-DHC) is an isomer of the cholesterol precursor 7-DHC (Item No. 14612).{36903,36904,35287} It accumulates in tissues and plasma in patients with Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in DHCR7, the gene encoding 3B-hydroxysterol-d7-reductase, and decreased cholesterol levels in bodily tissues and fluids, as well as microcephaly, intellectual disability, and distinctive dysmorphic features. 8-DHC levels are increased in serum in a rat model of SLOS induced by the DHCR7 inhibitor AY 9944 (Item No. 14611).{36903}
Specifications
CAS number
70741-38-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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8-dehydro Cholesterol

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