(+)-Cedrol

(+)-Cedrol is a sesquiterpene alcohol that has been used in Cannabis testing and has diverse biological activities.{42271} It inhibits the growth of L. sulphureus, G. trabeum, L. betulina, and T. versicolor wood decay fungi when used at a concentration of 100 ?g/ml.{36905} (+)-Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 ?M, respectively).{36906} In vivo, (+)-cedrol (200 mg/kg) prevents hair follicle dystrophy and reduces hair loss in a mouse model of alopecia induced by cyclophosphamide (Item No. 13849).{36907} (+)-Cedrol-loaded nanostructured lipid particles reduce peritoneal mast cell degranulation, a component of the type I anaphylactic response, induced by compound 48/80 (Item No. 22173) in mice.{36908}