1,2-Diheptanoyl-sn-glycero-3-PC

1,2-Diheptanoyl-sn-glycero-3-PC (DHPC-C7) is a synthetic phosphatidylcholine containing the short-chain (7:0) heptanoic acid at the sn-1 and sn-2 positions. It is commonly used in the formation of lipid bilayers and mixed micelles that has a critical micelle concentration (CMC) of 1.6 mM.{41970,41971} Short-chain phospholipids, such as DHPC-C7 and 1,2-dihexanoyl-sn-glycero-PC (DHPC-C6; Item No. 25585), increase the formation rate of substrate-supported planar phospholipid bilayers on glass and silica.{41971} DHPC-C7 inhibits insulin fibril formation in vitro in a concentration-dependent manner and inhibits cytotoxicity induced by insulin fibril formation in PC12 and SH-SY5Y cells when used at concentrations ranging from 0.5 to 4 mM.{41972}