Product description
3,4-Dicaffeoylquinic acid (3,4-DCQA) is a polyphenol with diverse biological activities.{41896,41897,41898,41899} 3,4-DCQA (1-500 ?g/ml) inhibits acetylcholinesterase (ACE) and a-glucosidase in a concentration-dependent manner.{41896,41898} It reduces mutagenicity of Trp-P-1 against S. typhimurium by 59% when used at a concentration of 0.57 mM.{41897} 3,4-DCQA has antioxidant activity in ferric reducing, B-carotene bleaching, and DPPH scavenging assays (EC50s = 2.18, 23.85, and 68.91 ?g/ml, respectively).{41898} It is cytotoxic to NCI-H23 lung adenocarcinoma cells (EC50 = 3.26 ?g/ml). In vivo, 3,4-DCQA (50 mg/kg) increases tumor necrosis factor-related apoptosis inducing ligand (TRAIL) mRNA, reduces influenza H1N1 hemagglutinin (HA) mRNA, and increases survival in a mouse model of influenza A infection.{41899}
Specifications
CAS number
14534-61-3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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