Product description
(-)-Borneol is a bicyclic monoterpene originally found in A. canadense.{36773,36774} It is a positive allosteric modulator of a1B2y2L subunit-containing GABAA receptors with an EC50 value of 237 µM for human recombinant receptors expressed in X. laevis oocytes.{36773} It increases the latency to first pentylenetetrazole- and maximal electroshock-induced seizure in mice when administered at doses of 50, 100, and 200 mg/kg.{36775} (-)-Borneol (300 mg/kg) also increases the permeability of the blood-brain barrier and increases the concentration of cisplatin reaching tumors in a mouse model of glioblastoma multiforme.{36776} Formulations containing (-)-borneol have been used as fragrance ingredients.
Specifications
CAS number
464-45-9
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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(-)-Borneol

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