Product description
3-Methylcrotonyl glycine (3-MCG) is a metabolite found in the urine of patients with 3-methylcrotonyl glycinuria, a metabolic disorder characterized by a deficiency in 3-methylcrotonyl-CoA carboxylase, that has diverse biological activities.{36412,36413} It inhibits CO2 production and mitochondrial complex II-III and creatine kinase activity in rat cerebral cortex preparations in a concentration-dependent manner.{36413} It also inhibits the Na+/K+-ATPase in purified synaptic membranes from rat cerebrum, indicating a potential role for this metabolite in the development of CNS damage associated with 3-methycrotonyl glycinuria.
Specifications
CAS number
33008-07-0
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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3-Methylcrotonyl Glycine

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3-Methylcrotonyl Glycine

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