Product description
10-PAHSA 13C4 is an isotopically enriched form of the polyunsaturated fatty acid 10-PASHA (Item No. 19973) with carbon-13 incorporated at positions 1, 2, 3, and 4. It is intended for use as an internal standard for the quantification of 10-PAHSA by GC- or LC-MS. 10-PAHSA is a newly identified endogenous lipid that belongs to a collection of branched fatty acid esters of hydroxy fatty acids (FAHFAs). It is a FAHFA in which palmitic acid (Item No. 10006627) is esterified to 10-hydroxy stearic acid. Among the FAHFA family members, PAHSAs are the most abundant in the adipose tissue of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.{27644} As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 10-PAHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.
Specifications
CAS number
2705244-93-3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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