Product description
(1R,9S)-(-)-B-Hydrastine is an enantiomer of the alkaloid hydrastine that inhibits dopamine biosynthesis (IC50 = 20.7 µM in PC12 cells) by inhibiting tyrosine hydroxylase activity.{38222,38223} It inhibits dopamine release with an IC50 value of 66.5 µM in the presence of high extracellular K+ levels. It also inhibits L-type and caffeine-activated store-operated Ca2+ channels and prevents Ca2+ leakage from intracellular stores.{38224,38225}
Specifications
CAS number
118-08-1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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(1R,9S)-(-)-B-Hydrastine

22363-10

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(1R,9S)-(-)-B-Hydrastine

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