Product description
4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities.{38612,38613,38614,38615,38616} It inhibits transport of pyridoxine (Item No. 20706), pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells.{38612} DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells.{38613} DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos.{38614} It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy.{38615} DOP reduces TNF-a and IL-6 production in mice infected with T. spiralis.{38616}
Specifications
CAS number
148-51-6
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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4-deoxy Pyridoxine (hydrochloride)

21863-100

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4-deoxy Pyridoxine (hydrochloride)

21863-100

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