Product description
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA (Item No. 90310) with antiproliferative and PPARy agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 µM, however it increased proliferation of MCF-7 cells.{34687} 4-oxo DHA binds covalently to PPARy and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 µM.{16872}
Specifications
CAS number
845673-74-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-80°C

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