Product description
(+-)-Nornicotine is an active metabolite of nicotine (Item No. 16535) and a nicotinic acetylcholine receptor (nAChR) agonist.{34465} It induces currents in Xenopus oocytes expressing human a7 nAChRs or a6 subunit-containing nAChRs (EC50s = 17 and 3.7 µM, respectively). (+-)-Nornicotine promotes cell migration and destabilizes cell-cell junctions in EA.hy926 endothelial cells.{34463} It is self-administered in rats.{34462,34464}
Specifications
CAS number
5746-86-1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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