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Mouse Monoclonal to CD22 / BL-CAM, Clone IS7, PE
1P-506-T100
100 tests
€367
Product description
CD22, also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2,6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs), thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
IS7
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C
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Productname
Mouse Monoclonal to CD22 / BL-CAM, Clone IS7, PE
1P-506-T100
By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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Productname
Mouse Monoclonal to CD22 / BL-CAM, Clone IS7, PE
1P-506-T100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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