Product description
CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
LT27
Isotype
Mouse IgG2a
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C

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Mouse Monoclonal to CD27, Clone LT27, PE

1P-308-T100

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Productname

Mouse Monoclonal to CD27, Clone LT27, PE

1P-308-T100

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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