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Anti-Hu CD7 PE
1P-206-T100
100 tests
€283
Product description
CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
MEM-186
Isotype
Mouse IgG1
Supplier
Exbio
Product status
RUO
Shipping & storage
Storage temperature
2-8°C
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Anti-Hu CD7 PE
1P-206-T100
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Anti-Hu CD7 PE
1P-206-T100
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