Product description
CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
LT95
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C

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Productname

Mouse Monoclonal to CD95 / Fas, Clone LT95, FITC

1F-362-T100

By filling out this form, you are placing an order by e-mail. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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Productname

Mouse Monoclonal to CD95 / Fas, Clone LT95, FITC

1F-362-T100

By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.


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