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Mouse Monoclonal to CD7 / gp40, Clone MEM-186, APC
1A-206-T100
100 tests
€283
Product description
CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.
Specifications
Applications
FC
Host
Mouse
Clonality
Monoclonal
Clone
MEM-186
Isotype
Mouse IgG1
Supplier
Exbio
Shipping & storage
Storage temperature
2-8°C
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Productname
Mouse Monoclonal to CD7 / gp40, Clone MEM-186, APC
1A-206-T100
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Productname
Mouse Monoclonal to CD7 / gp40, Clone MEM-186, APC
1A-206-T100
By filling out this form, you request a sample. You will receive an order confirmation within one working day. The order cannot be modified after receipt of the order confirmation.
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