(+-)-Taxifolin

(+-)-Taxifolin is a flavonoid that has been found in M. butyracea and has diverse biological activities.{56219,30238,30239,30237} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in cell-free assays.{56219} (+-)-Taxifolin is cytotoxic to HCT116 cells (IC50 = 63.42 µM).{30238} It inhibits HMG-CoA reductase activity and cholesterol synthesis in HepG2 cells by 47 and 86%, respectively, when used at a concentration of 200 µM.{30239} In vivo, (+-)-taxifolin reduces carrageenan-induced paw edema in rats (ED50 = 12.9 mg/kg).{32037}