(+-)-4-hydroxy Propranolol (hydrochloride)

Propranolol inhibits B1-, B2-, and B3-adrenergic receptors with log KD values of -8.16, -9.08, and -6.93, respectively.{25151,25396} (+-)-4-hydroxy Propranolol is an active metabolite of propranolol, inhibiting B1- and B2-adrenergic receptors with KD values of 2.4 and 5.8 nM, respectively.{30091,30093} It is comparable to propranolol in potency in antagonizing the effects of isoprenaline on heart rate and blood pressure in cats and dogs.{30091,30090} (+-)-4-hydroxy Propranolol also has antioxidant properties at micromolar concentrations.{30092}