Product description
CD104 represents the integrin ?4 subunit that associates non-covalently with integrin ?6 (CD49f) to form the ?6?4 integrin heterodimer. The ?6?4 complex is expressed on the basal surface of a variety of epithelial cell types particularly on stratified squamous epithelia. It is also found in peripheral nerves, in certain subsets of endothelial cells, and on immature thymocytes. It also has been found to be associated with a number of malignant tissues. Hemidesmosomal ?6?4 plays an important role in the adhesion of epithelial cells to basement membranes via interactions with laminin and/or kalinin anchoring filaments. It is not known if the monoclonal antibody 346-11A can block this adhesion.
Specifications
Applications
FC, IP, IHC, WB, ICC
Host
Rat
Clonality
Monoclonal
Clone
346-11A
Isotype
IgG2a
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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Rat Anti-Mouse CD104-UNLB

1855-01

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Rat Anti-Mouse CD104-UNLB

1855-01

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