Product description
(+-)-Ibuprofen-d3 is intended for use as an internal standard for the quantification of ibuprofen by GC- or LC-MS. (+-)-Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) and non-selective COX inhibitor (IC50s = 2.6 and 1.3 µM for human recombinant COX-1 and COX-2, respectively).{1364} In vivo, (+-)-ibuprofen inhibits late-phase formalin-induced paw licking in mice (ED50 = 6.1 mg/kg).{57951} It also inhibits acetic acid-induced writhing in mice (ED50 = 0.47 mg/kg). Formulations containing (+-)-ibuprofen have been used in the treatment of fever and mild to severe pain.
Specifications
CAS number
121662-14-4
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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