Product description
2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide is a sulfide-like inhibitor of phosphodiesterase 7 (PDE7; IC50 = 2.1 µM).{29363} It is selective for PDE7A, producing only 10-11% inhibition of PDE3A, PDE4D, and PDE4B at 10 µM.{29363} It also has no antioxidant activity or inhibitory activity against a panel of protein kinases.{29363} Sulfide-like PDE7 inhibitors derived from 2-acetamidophenyl 5-chloro-2-nitrophenyl sulfide have cytoprotective and anti-inflammatory effects on SH-SY5Y neuroblastoma cells without action in a surrogate emesis mouse model.{29363}
Specifications
CAS number
107522-19-0
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide

18085-1

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2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide

18085-1

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