Product description
1-Deoxymannojirimycin is a specific inhibitor of class I a-1,2-mannosidase (IC50 = 0.02 µM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome.{28144,28145} By inhibiting a-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.{28146,28147}
Specifications
CAS number
73465-43-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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1-Deoxymannojirimycin (hydrochloride)

17178-1

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1-Deoxymannojirimycin (hydrochloride)

17178-1

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