(-)-Gallocatechin ((-)-GC) is an epimer of (-)-epigallocatechin ((-)-EGC; Item No. 11809). They are flavan-3-ols and members of the catechin family of polyphenolic antioxidants found in green tea and other plant extracts.{23119} Both (-)-GC and (-)-EGC are potent antioxidants and significantly inhibit the proliferation of HCT116 and SW480 cancer cells.{23115,27615,23119} (-)-GC also inhibits the aggregation of amyloid B peptide in vitro (IC50 = 17.5 µM).{27617} With increasing temperature, the steaming of green tea leaves results in the reduction of 2,3-cis isomers, like (-)-EGC, and an increase in 2,3-trans isomers, like (-)-GC.{27615,27616}