Product description
1-Azakenpaullone is an analog of kenpaullone (Item No. 10010239) that inhibits glycogen synthase kinase 3B (GSK3B) more potently (IC50 = 18 nM) than CDK1/cyclin B or CDK5/p25 (IC50s = 2.0 and 4.2 µM, respectively).{27328} Through its effects on GSK3B, 1-azakenpaullone stimulates the proliferation of human pancreatic islets and drives the differentiation of mouse embryonic stem cells and Nematostella larvae.{27329,27331,27330}
Specifications
CAS number
676596-65-9
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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