Product description
8-iso Prostaglandin F2a (8-iso PGF2a; 8-isoprostane) is a prostaglandin-like product of non-specific lipid peroxidation.{320} 2,3-dinor-8-iso PGF2a is a metabolite of 8-iso PGF2a in humans and rats.{6907} In these species, exogenously infused 8-iso PGF2a is converted to 2,3-dinor-8-iso PGF1a and (2,3-dinor-8-iso PGF2a.{6907,3026} Rat hepatocytes further metabolize 8-iso PGF2a to another B-oxidation product, 2,3,4,5-tetranor-8-iso PGF2a.{6907} 2,3-dinor-8-iso PGF2a is present in normal human urine at concentrations of 200-300 pg/ml.{6907} Its concentration is increased in conditions of oxidative injury (for example, smoking), and correlates well with that of the parent isoprostane, 8-iso PGF2a.{6907}
Specifications
CAS number
221664-05-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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2,3-dinor-8-iso Prostaglandin F2a

16290-100

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