Product description
In addition to its role in the Krebs cycle, a-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes. 5-Octyl-a-ketoglutarate, also known as a-ketoglutarate octyl ester, is a stable, cell-permeable molecule that generates free a-ketoglutarate upon hydrolysis of the ester bond by cytoplasmic esterases.{21289} It is used in experiments to increase levels of intracellular a-ketoglutarate.{21289} 5-Octyl-a-ketoglutarate has been shown to modulate a variety of enzymes and signaling pathways, particularly in the context of glycolysis, hypoxia, and cancer.{21289,26774,27744,27745,26069}
Specifications
CAS number
1616344-00-3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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5-Octyl-a-ketoglutarate

16105-5

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5-Octyl-a-ketoglutarate

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