Product description
CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. The monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3.
Specifications
Applications
FC, IHC
Host
Rat
Clonality
Monoclonal
Clone
6D5
Isotype
IgG2a
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C

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Rat Anti-Mouse CD19-CY5

1575-15

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Rat Anti-Mouse CD19-CY5

1575-15

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