Product description
CD11b (integrin ?M subunit) combines with CD18 (integrin ?2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
Specifications
Applications
FC, IP, IHC, ICC
Host
Rat
Clonality
Monoclonal
Clone
3A33
Isotype
IgG2a
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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Rat Anti-Mouse CD11b/Mac-1a-LE/AF

1560-14

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Productname

Rat Anti-Mouse CD11b/Mac-1a-LE/AF

1560-14

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