Product description
2-hexyl-4-Pentynoic acid is a derivative of valproic acid (Item No. 13033), an inhibitor of histone deacetylases (HDACs). It inhibits HDAC activity more potently (IC50 = 13 µM) than valproic acid (IC50 = 398 µM).{24558} 2-hexyl-4-Pentynoic acid induces histone hyperacetylation in cerebellar granule cells significantly at 5 µM.{24558} It also induces the expression of heat shock proteins Hsp70-1a and Hsp70-1b and protects cerebellar granule cells from glutamate-induced excitotoxicity when used at a concentration of 50 µM.{24558}
Specifications
CAS number
96017-59-3
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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