1,2-Dipalmitoyl-sn-glycero-3-PE

1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally-occurring PE containing 16:0 fatty acids at the sn-1 and sn-2 positions. It belongs to a class of phospholipids that are the most abundant lipids in the inner leaflet of the plasma membrane.{24442} 1,2-DPPE interacts with cholesterol to form a condensed lipid monolayer with tight hydrogen bonding of the 1,2-DPPE interheadgroups, resulting in a more fluid membrane that may aid in transport and signaling across the bilayer.{24262,24261}