Product description
The liver x receptors (LXRa and LXRB) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism.{12040} 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRa and LXRB in vitro with EC50 values of 85 and 71 nM, respectively, and is a potent suppressor of cholesterol biosynthesis.{13891,23747} 25(S)-27 hydroxy Cholesterol is the less predominant-occurring (~20%) stereoisomer of the endogenous oxysterol 27-hydroxy cholesterol.{23746,23745}
Specifications
CAS number
56845-83-1
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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25(S)-27-hydroxy Cholesterol

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