Product description
(+)-Pilocarpine is a muscarinic acetylcholine receptor agonist that binds to human hippocampal, pons, and submandibular gland membranes, which are endogenously enriched in the M1, M2, and M3 receptor subtypes, respectively (apparent Kis = 6, 8.2, and 6.9 ?M, respectively).{48747} It induces salivary secretion in rats when administered intraperitoneally at a dose of 1 mg/kg.{48748} Topical administration of (+)-pilocarpine inhibits methylcellulose-induced increases in intraocular pressure in rabbits in a dose-dependent manner.{48749} (+)-Pilocarpine is a chemoconvulsant that has been used in the generation of temporal lobe epilepsy animal models.{52179,26629,23165} Formulations containing (+)-pilocarpine have been used in the treatment of elevated intraocular pressure and dry mouth.
Specifications
CAS number
54-71-7
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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(+)-Pilocarpine (hydrochloride)

14487-10

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(+)-Pilocarpine (hydrochloride)

14487-10

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