Product description
The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis.{22577} 1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50 = 0.39 ?M).{22573} It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death.{22579,22576,22574} This compound can be used with cells in culture and in animals.{22576,22575,22578}
Specifications
CAS number
9-2-5154
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Blue Ice
Storage temperature
2-8°C

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1,5-Isoquinolinediol

14438-5

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