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Induction of TLR3 activity by poly(I:C) in TLR3/IFNBr Leeporter™ - HEK293 cells.
Product description
The TLR3/IFNB Leeporter™ Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses full-length human Toll-like receptor 3 (TLR3) and Renilla luciferase reporter gene under the transcriptional control of the human IFN-beta (IFNB) promoter. Functional activity of the cell line has been validated by TLR3 ligand assay (Figure 1), in which upon activation by poly (I:C), TLR3 quickly initiates TRIF-dependent signaling pathway and mediates nuclear translocation of IRF3 that induces IFNB promoter activity.The TLR3/IFNB activation by poly(I:C) is shown in Figure 1. 
Specifications
Applications
FUNC
Supplier
Abeomics
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-196°C

Price on Request

Productname

TLR3/IFNB Leeporter HEK293 Cell Line

14-122ACL


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