Product description
LSF, a chiral metabolite of pentoxifylline, acts as a potent anti-inflammatory agent.{17416,18148} (S)-LSF is the pharmacologically inactive optical enantiomer of (R)-LSF, the biologically active isomer.{18148} When metabolized by isolated human liver cells, pentoxifylline is exclusively reduced to (S)-LSF in the cytosol, while reduction in liver microsomes is 85% stereoselective in favor of (S)-LSF formation.{18149} Thus, pentoxifylline is an inefficient prodrug for the delivery of therapeutically relevant lisofylline.
Specifications
CAS number
100324-80-9
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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