Product description
Equol is a nonsteroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora.{16628,16720} The estrogen receptor (ER) binding activity of the naturally occurring (S)-enantiomer demonstrates greater affinity toward ERB while the (R)-enantiomer demonstrates greater affinity towards ERa.{16628,16720} Synthesized as a racemic mixture, (+-)-equol exhibits EC50 values of 200 and 74 nM for human ERa and ERB, respectively and induces breast cancer cell proliferation in vitro at concentrations as low as 100 nM.{16720,17383}
Specifications
CAS number
94105-90-5
Supplier
Cayman Chemical
Shipping & storage
Shipping condition
Dry Ice
Storage temperature
-20°C

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