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Product description
Tollip, also known as Toll interacting protein, is a 30 kDa ubiquitin-binding protein that is a component of the signaling pathway of IL-1 and Toll-like receptors. It performs multiple functions and is classified as an adaptor protein. Tollip interacts with IRAK-1 (IL-1 receptor-associated kinase 1) prior to IL-1? stimulation and suppresses the kinase activity of IRAK-1. Tollip also associates with Tom1 forming a complex which regulates endosomal trafficking of ubiquitinated proteins.
Specifications
Applications
FC, WB, ELISA
Host
Mouse
Clonality
Monoclonal
Clone
SB40a
Isotype
IgG2a
Supplier
Southern Biotech
Shipping & storage
Shipping condition
Room Temperature
Storage temperature
2-8°C