An inhibitor of MAGL (IC50s = 3.7, 7.6, and 14 nM for the human, mouse, and rat enzymes, respectively); selective for MAGL over FAAH (IC50s = 20.6, 31, and 14 µM for the human, mouse, and rat enzymes, respectively) and ABHD6 (IC50s = 107 and 50 nM for the mouse and rat enzymes, respectively)
Productname
JW 642
11789-5
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